Where Science Meets Recovery
Advancing evidence-based nervous system recovery through rigorous clinical investigation of twelve integrative therapeutic modalities.
Modalities
Analyzed
IRB Studies
Our Mission
Where science meets recovery.
"Our clients are running billion-dollar products, raising Series B rounds, managing hundreds of people — and they're doing it on a dysregulated nervous system. That's not a wellness problem. That's a performance problem. We measure it like one."— Natasha Berness, Founder & Research Director
HRV Baseline Data
The Landscape
The recovery gap.
Anxiety disorders affect 40M Americans. Chronic stress costs $300B annually. Yet fewer than 5% of wellness programs address the root cause: autonomic dysregulation.
Research Domains
Twelve modalities. One system.
SRI investigates the mechanisms, efficacy, and optimal protocols for twelve evidence-informed therapeutic modalities. All evaluated, published, and optimized as a unified recovery system.
Float Therapy (REST)
Restricted Environmental Stimulation Therapy reduces sensory input to induce deep relaxation. Meta-analyses show significant reductions in anxiety, depression, and pain.
Contrast Therapy
Alternating heat and cold triggers hormesis — adaptive stress responses that strengthen cardiovascular and immune function. HRV improves 10-20% over 6 weeks.
Pressotherapy
Computer-controlled compression therapy enhances lymphatic drainage and circulation. Meta-analyses demonstrate efficacy for edema and post-exercise recovery.
Halotherapy
Dry salt aerosol inhalation improves respiratory function through mucociliary clearance and anti-inflammatory mechanisms.
Red Light Therapy
Low-level red and near-infrared light stimulates mitochondrial ATP production. FDA-cleared for pain relief, hair growth, and skin conditions.
EMTT & PEMF
Electromagnetic field therapy stimulates cellular repair and modulates inflammation. Multiple RCTs demonstrate efficacy for pain and tissue healing.
ZYTO Biofeedback
Galvanic skin response technology measures autonomic nervous system reactions against 168 digital biomarkers across 6 wellness categories. FDA-cleared.
Breathwork
Guided breathing protocols regulate the autonomic nervous system, improving HRV, reducing cortisol, and building stress resilience across contexts.
Neurofeedback
Real-time brainwave training using EEG feedback to modulate attention, anxiety, and peak cognitive performance states.
Infrared Sauna
Deep-penetrating infrared heat induces cardiovascular stress similar to moderate exercise, promoting detoxification and pain relief.
Sound Healing
Vibrational and frequency-based therapy using tuning forks, singing bowls, and binaural beats to modulate heart rate coherence.
Bioenergetics
Assessment of the body's energetic field and meridian system, exploring correlations between energy patterns and physiological states.
Clinical Evidence
Evidence, not opinion.
SRI maintains a living database of clinical evidence across all twelve therapeutic modalities, evaluated using GRADE criteria and updated monthly.
| Modality | Evidence Level | Key Conditions | Studies | Effect Size |
|---|---|---|---|---|
| Float Therapy (REST) | Strong | Anxiety, Depression, Pain, PTSD | 63+ | Large (d=0.7-1.2) |
| Contrast Therapy | Strong | Cardiovascular, Recovery, Mood | 75+ | Moderate-Large |
| Pressotherapy | Strong | Edema, Circulation, Recovery | 25+ | Moderate |
| Halotherapy | Moderate | Asthma, COPD, Rhinitis | 20+ | Small-Moderate |
| Red Light Therapy | Strong | Pain, Skin, Hair, Recovery | 1,000+ | Moderate |
| EMTT & PEMF | Strong | Pain, Tissue Repair, Inflammation | 65+ | Moderate-Large |
| ZYTO Biofeedback | FDA-Cleared | Stress, Wellness, Biomarkers | 168 | GSR Technology |
| Breathwork | Strong | Anxiety, HRV, Stress | 80+ | Moderate-Large |
| Neurofeedback | Moderate | ADHD, Anxiety, Performance | 100+ | Moderate |
| Infrared Sauna | Strong | Cardiovascular, Pain, Detox | 40+ | Moderate-Large |
| Sound Healing | Emerging | Stress, Anxiety, Sleep | 10+ | Small-Moderate |
| Bioenergetics | Emerging | Stress, Energy, Wellness | 5+ | Emerging |
SRI updates this database monthly. All studies evaluated using GRADE criteria. Effect sizes reported as Cohen's d.
The Study
Protocol NSR-2026.
A 12-week multimodal intervention measuring autonomic regulation through continuous HRV monitoring, pre/post biometric assessment, and validated psychological instruments.
NeuroScore Composite
A proprietary composite index integrating HRV (time and frequency domain), sleep architecture, inflammatory markers, and self-reported wellness scores into a single 0-100 metric.
Baseline Assessment
Comprehensive biometric profiling including 24-hour HRV, cortisol awakening response, inflammatory markers, and validated psychological instruments.
Intervention Protocol
Personalized multimodal program delivered across 12 weeks with weekly biometric monitoring and protocol adjustments based on real-time data.
Midpoint Analysis
6-week biometric reassessment with comparative analysis against baseline. Protocol refinements implemented for non-responders.
Outcome Evaluation
Final biometric and psychological assessment. 3-month and 6-month follow-up tracking for sustainability analysis.
Funding
Fund the future.
SRI welcomes research grants, corporate partnerships, and collaborative investigations. All research operates under IRB oversight with open-access publication commitment.
Primary 12-week multimodal intervention study. 200 participants. Continuous HRV monitoring.
NeuroScore algorithm refinement and real-time biometric dashboard development.
2-year follow-up study tracking sustained autonomic regulation improvements.
Total Active Grant Requirement: $450,000 over 18 months
Grantmakers, institutions, and corporate wellness programs: contact us to discuss research partnerships.
Request Grant ProposalPeople
The team behind the science.
Former Big 4 management consultant and senior executive at IBM, EY, Deloitte, LinkedIn, Charles Schwab, and Levi Strauss & Co. After experiencing severe burnout, Natasha pivoted to holistic healing, studying biohacking, longevity science, and nervous system regulation. She leads SRI's research agenda and clinical protocol development.
Former lead senior designer at Oracle and marketing executive at multiple Silicon Valley startups. Anna drives SRI's digital experience, data visualization, and technology innovation.
Physician, Palo Alto. Board-certified in internal medicine with specialization in integrative health approaches and autonomic dysfunction.
PhD Neuroscience, Stanford. Specializes in neuroplasticity research and non-invasive neuromodulation techniques.
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Join a Study
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Grantmakers, institutions, and corporate partners: let's discuss how we can advance nervous system recovery science together.
Inquiry Received
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